Can CoQ10 Help Lower Blood Pressure?

One out of every three people in the United States has high blood pressure, according to the Centers for Disease Control and Prevention (CDC).1 It is one of the major risk factors for stroke and heart attack. Hypertension, another word for high blood pressure, is a major public health concern because only about half of those diagnosed have it under control. This means many people could use help in controlling their blood pressure more effectively.

What is CoQ10?

CoQ10, a naturally occurring antioxidant found in almost every cell in the body, is believed to have the potential to help manage blood pressure. There have been several clinical trials on CoQ10 and hypertension and although there are some promising results, at this time the research remains inconclusive.

How Can CoQ10 Lower Blood Pressure?

Right now, CoQ10 is theorized to lower blood pressure through a few different mechanisms. First, it is an antioxidant, meaning it helps reduce oxidative stress, which may in turn lower blood pressure. Second, it has been shown to improve the function of the mitochondria, or energy source of the cells, which has been associated with a decrease in blood pressure. Finally, it has a slight vasodilation effect, relaxing the blood vessels, and in turn lowering blood pressure.2

    Research on CoQ10 for High Blood Pressure

    Looking at the current research, there have been several studies supporting the use of CoQ10 as a way to help manage blood pressure, including two meta-analyses that showed statistically significant improvements.

    A 2007 meta-analysis of 12 clinical trials concluded that supplementation with CoQ10 lowered systolic blood pressure by up to 17 mm Hg and diastolic by 10 mm Hg.3 Then in 2018, a meta-analysis of 17 studies found that CoQ10 significantly decreased systolic blood pressure, but not diastolic blood pressure.4 Based on findings of these two meta-analyses, CoQ10 does seem to have some effect on helping lower blood pressure.

    Click here to access the 2018 meta-analysis

    Similar results have been found in pregnant women with preeclampsia, a dangerous form of hypertension that only happens during pregnancy. Women who took a CoQ10 supplement during pregnancy had a significantly lower chance of developing preeclampsia.5

    The study can be found here

    But, not all trials have been as conclusive as those mentioned above. A 2016 review identified two small studies, including about 50 subjects, that found no evidence that supplementation of CoQ10 helped lower hypertension.6

    Here is a link to the study

    If you have high blood pressure, should you try a CoQ10 supplement? The research is mixed, but promising. One thing to note is that in all the studies mentioned, there were very few side effects found with CoQ10 supplements. The important thing with any supplement regimen is to always ask your doctor before starting to make sure it is safe for your specific health condition.



    1 High Blood Pressure (Hypertension) Information | Published 2018 

    2 Nutrition. 2010;26(3):250-254.

    J Hum Hypertens. 2007;21(4):297-306

    High Blood Pressure & Cardiovascular Prevention. 2018;25(1):41-50

    International Journal of Gynecology & Obstetrics. 2009;107:S358-S358

    Cochrane Database of Systematic Reviews. 2016


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    • Blog Contributor
    Comments 2
    • Eric Drew
      Eric Drew

      Thank you! Very valuable content in a clear concise write up!

    • Jim Plant
      Jim Plant

      Take coq10 every day. I feel it helps with oxygen levels in the blood. I live at 7800 ft in colorado.

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