New Research Shows Favorable Response To Statin Withdrawal and CoQ10 Initiation
As heart failure becomes increasingly more common, even in people who have been taking statins for a long period of time, the need to discover alternative treatment arises.
In the most recent research to date, scientists specializing in heart health tested the efficacy of CoQ10 supplements on 142 heart failure patients. These people, in spite of receiving long-term statin therapy, had developed heart failure “in the absence of any identifiable cause.” Their statin medication was replaced with a 300-mg daily supplement of CoQ10.1
At the beginning of the study, 94% of the test subjects presented with preserved ejection fraction, and 6% with reduced ejection fraction. These are two stages of heart failure that affect the diastolic function or pumping-action of the left ventricle of the heart. Preserved EF and reduced EF both limit the amount of blood your body receives with each beat of the heart. This condition can also lead to a stiffening of the heart muscle.
Over the course of about three years, the test subjects were given physical examinations to follow their progress and to record their health outcomes based on these findings:
- Symptom scores
- Plasma CoQ10
- Cholesterol levels
With daily supplementation of CoQ10, test subjects experienced some critical improvements in their heart health. By the end of the study, in heart failure patients with:
- Preserved EF, 34% had normalization of diastolic function, and 25% showed improvement;
- Reduced EF, ejection fraction improved from a mean of 35% to 47%.
In addition, heart failure symptoms improved from 8% to 79% of patients at the time of their final follow-up examination, placing them into the Class I category with no symptoms and no limitation in ordinary physical activity.
Similarly, CoQ10 supplementation significantly improved statin-attributable symptoms, such as fatigue, muscle weakness, myalgias, memory loss, and peripheral neuropathy. The proportion of patients with:
- No muscle weakness increased from 39% at baseline to 92% at final follow-up;
- No memory loss increased from 27% at baseline to 72% at final follow-up.
The report concluded that the majority of heart failure patients responded safely to the discontinuation of statin medications and the initiation of CoQ10 supplementation. The scientists also pointed out that heart failure may develop in patients receiving long-term statin therapy, along with other statin-attributable adverse effects, and that physicians need to be aware of safe alternatives like CoQ10 supplementation.
Coenzyme Q10, or CoQ10 for short, is a naturally occurring nutrient-like coenzyme that plays a key role in 95% of your body’s energy production. Your heart muscle is the biggest producer and consumer of energy, and requires vast amounts of CoQ10 to function optimally. Because of its many heart health benefits, CoQ10 is recommended by more cardiologists than any other supplement, especially patients taking cholesterol-lowering statin medications.*
For more information, read: Four Reasons Why You Should be Taking a CoQ10 Supplement.
* lQVIA ProVoice Survey
- Blog Contributor