New Research Shows Favorable Response To Statin Withdrawal and CoQ10 Initiation

New Research Shows Favorable Response To Statin Withdrawal and CoQ10 Initiation


As heart failure becomes increasingly more common, some doctors are starting to recommend CoQ10 to those taking a statin drug. However, before starting any new supplement, it is important to talk to your doctor about your specific health concerns so they can determine the best treatment options. 

In a recent study, scientists specializing in heart health tested the efficacy of CoQ10 supplements on 142 heart failure patients. These people, in spite of receiving long-term statin therapy, had developed heart failure “in the absence of any identifiable cause.” Their statin medication was replaced with a 300-mg daily supplement of CoQ10.1

At the beginning of the study, 94% of the test subjects presented with preserved ejection fraction, and 6% with reduced ejection fraction. These are two stages of heart failure that affect the diastolic function or pumping-action of the left ventricle of the heart. Preserved EF and reduced EF both limit the amount of blood your body receives with each beat of the heart. This condition can also  lead to a stiffening of the heart muscle.

Over the course of about three years, the test subjects were given physical examinations to follow their progress and to record their health outcomes based on these findings:

  • Symptom scores
  • Echocardiograms
  • Plasma CoQ10
  • Cholesterol levels

With daily supplementation of CoQ10, test subjects experienced some critical improvements in their heart health. By the end of the study, in heart failure patients with:

  • Preserved EF, 34% had normalization of diastolic function, and 25% showed improvement;
  • Reduced EF, ejection fraction improved from a mean of 35% to 47%.

In addition, heart failure symptoms improved from 8% to 79% of patients at the time of their final follow-up examination, placing them into the Class I category with no symptoms and no limitation in ordinary physical activity.

Similarly, CoQ10 supplementation significantly improved statin-attributable symptoms, such as fatigue, muscle weakness, myalgias, memory loss, and peripheral neuropathy. The proportion of patients with:

  • No muscle weakness increased from 39% at baseline to 92% at final follow-up;
  • No memory loss increased from 27% at baseline to 72% at final follow-up.

The report concluded that in patients receiving long-term statin therapy, statin-associated cardiomyopathy may develop that responds safely to statin treatment discontinuation and CoQ10 supplementation. The scientists also pointed out that heart failure may develop in patients receiving long-term statin therapy, along with other statin-attributable adverse effects, and that physicians need to be aware of the potential benefits of coupling CoQ10 supplements with statin therapy. 

Coenzyme Q10, or CoQ10 for short, is a naturally occurring nutrient-like coenzyme that plays a key role in 95% of your body’s energy production. Your heart muscle is the biggest producer and consumer of energy, and requires vast amounts of CoQ10 to function optimally. Because of its many heart health benefits, CoQ10 is recommended by more cardiologists than any other supplement, especially patients taking cholesterol-lowering statin medications.*

For more information, read: Four Reasons Why You Should be Taking a CoQ10 Supplement.




* lQVIA ProVoice Survey



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      Comments 6
      • PAm COok
        PAm COok

        I take the turmeric in the morning with my meds and the COQ10 with a statin at night!

      • Harriet Anderson
        Harriet Anderson

        I have had surgery on my Heart. After surgery, With my first appointment to see my Cardiologist
        He wrote my statin order right along with CoQ10. This has been very helpful for me.
        My Cardiologist also said CoQ10 may also be beneficial for my diagnosis of Fibromyalgia.

      • tim mccalman
        tim mccalman

        I played/competed in many sports, powerlifting and bodybuilding, martial arts, etc. for over 30 years. However, I had to give them all up due to chronic inflammation, which was leading to bone spurs in my shoulders and elbow. I was absolutely miserable and always in pain. Cortisone shots didn’t help and I had to have my left shoulder joint shaved to remove spurs. Then a friend introduced me to your turmeric supplements. After only one bottle of the capsules, I can move with nuch more pain free range of motion, and will be getting back in the gym! I’m back to doing lots of things I love, and will definitely continue to take the turmeric! Thanks so much for such a great product!

      • Sandra M. Classey
        Sandra M. Classey

        I find the liquid works the best for me

      • RDoherty

        Turmeric is more of an antiseptic, anti-inflammatory, antioxidant. Completely different from CoQ10. So no it wont replace the benefits youre receiving from the CoQ10 but i would keep the turmeric and take them both, its also a very beneficial supplement

      • Kitty Jaramillo
        Kitty Jaramillo

        I’ve been using CoQ10 daily and have felt so much better. Today I bought by mistake the Qunol liquid turmeric. Is there a big difference between them? Or can I expect the same benefits.

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